Difference between revisions of "Adenovirus"

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==Background==
 
==Background==
 +
*Medium-sized (90-100 nm), non-enveloped icosohedral viruses with double-stranded DNA
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*> 50 types of adenoviruses can cause infections in humans
 +
*Relatively resistant to common disinfectants and environmental conditions
  
 
==Clinical Features==
 
==Clinical Features==
 +
*Adenoviruses affect many different organ systems.
 +
**Most commonly respiratory ill
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***[[Common cold]], [[pneumonia]], [[croup]], and bronchitis
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**[[Gastroenteritis]]
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**[[Conjunctivitis]]
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**[[Cystitis]]
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**Less commonly central nervous system involvement
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*More severe infection in immunocompromised individuals
 +
*Transmitted primarily via respiratory droplets, but also by fecal routes
  
 
==Differential Diagnosis==
 
==Differential Diagnosis==
 +
Viral respiratory illness also caused by:
 +
*Rhinoviruses
 +
*Coronaviruses
 +
*Influenza viruses
 +
*Parainfluenza viruses
 +
*Enteroviruses
 +
*Human metapneumoviruses
 +
*RSV
  
==Diagnosis==
+
==Evaluation==
 +
*Typically clinical diagnosis after excluding other possible treatable infection
 +
*Antigen detection, PCR assay, virus isolation, and serology can be used to identify adenovirus infections, but the presence of virus does not necessarily mean it is associated with disease
  
 
==Management==
 
==Management==
 +
*No virus-specific treatment available
 +
*Symptomatic treatment only
 +
*No vaccine available to the public currently
 +
*Prevention with appropriate hand hygiene, infection control practices, and chlorinated pools
  
 
==Disposition==
 
==Disposition==
 +
*Commonly outpatient management
 +
*Death exceeding rare
 +
*Complications include necrotizing pneumonia and bronchiolitis obliterans
  
 
==See Also==
 
==See Also==
 
+
*[[Fever and rash]]
 +
*[[Upper respiratory infection]]
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*[[Gastroenteritis]]
 
==External Links==
 
==External Links==
  
 
==References==
 
==References==
<references/>
+
<CDC Adenoviruses for health care professionals. National Center for Immunization and Respiratory Diseases, Division of Viral Diseases. April 2015/>
  
 
[[Category:ID]]
 
[[Category:ID]]

Latest revision as of 18:09, 10 August 2016

Background

  • Medium-sized (90-100 nm), non-enveloped icosohedral viruses with double-stranded DNA
  • > 50 types of adenoviruses can cause infections in humans
  • Relatively resistant to common disinfectants and environmental conditions

Clinical Features

  • Adenoviruses affect many different organ systems.
  • More severe infection in immunocompromised individuals
  • Transmitted primarily via respiratory droplets, but also by fecal routes

Differential Diagnosis

Viral respiratory illness also caused by:

  • Rhinoviruses
  • Coronaviruses
  • Influenza viruses
  • Parainfluenza viruses
  • Enteroviruses
  • Human metapneumoviruses
  • RSV

Evaluation

  • Typically clinical diagnosis after excluding other possible treatable infection
  • Antigen detection, PCR assay, virus isolation, and serology can be used to identify adenovirus infections, but the presence of virus does not necessarily mean it is associated with disease

Management

  • No virus-specific treatment available
  • Symptomatic treatment only
  • No vaccine available to the public currently
  • Prevention with appropriate hand hygiene, infection control practices, and chlorinated pools

Disposition

  • Commonly outpatient management
  • Death exceeding rare
  • Complications include necrotizing pneumonia and bronchiolitis obliterans

See Also

External Links

References

<CDC Adenoviruses for health care professionals. National Center for Immunization and Respiratory Diseases, Division of Viral Diseases. April 2015/>