ACTH (cosyntropin) stimulation test: Difference between revisions

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*Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration
*Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration


== Treatment==
==Treatment==
*Then give either  
*Then give either  
**[[Dexamethasone]] 6mg IV  
**[[Dexamethasone]] 6mg IV  

Revision as of 18:01, 6 July 2016

Background

  • ACTH (cosyntropin) stimulation test measures how well the adrenal glands respond to adrenocorticotropic hormone (ACTH)
  • ACTH is a hormone produced in the pituitary gland that stimulates the adrenal glands to release a hormone called cortisol
  • Man-made form of ACTH is called cosyntropin

Test

  1. Before: Draw serum cortisol
  2. Time 0: Give ^0.25mg IM/IV of ACTH (Cosyntropin) over 2min
  3. Time 30: Draw serum cortisol
  4. Time 60: Draw serum cortisol & give 100mg hydrodortison IVP

^0.125mg if <2yrs old

  • Normal Response: Cortisol level doubles from baseline after Cosyntropin administration
  • Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration

Treatment

See Also

References