ACTH (cosyntropin) stimulation test: Difference between revisions

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==See Also==
==See Also==
*[[Adrenal crisis]]
*[[Adrenal crisis]]
*[[Addison's disease]]


==References==
==References==


[[Category:Endo]]
[[Category:Endo]]

Revision as of 22:41, 17 May 2015

Background

  • ACTH (cosyntropin) stimulation test measures how well the adrenal glands respond to adrenocorticotropic hormone (ACTH)
  • ACTH is a hormone produced in the pituitary gland that stimulates the adrenal glands to release a hormone called cortisol
  • Man-made form of ACTH is called cosyntropin

Test

  • ACTH (Cosyntropin)
  1. Before: Draw serum cortisol
  2. Time 0: ^0.25mg IM/IV over 2min
  3. Time 30: Draw serum cortisol
  4. Time 60: Draw serum cortisol & give 100mg hydrodortison IVP

^0.125mg if <2yrs old

  • Normal Response: Cortisol level doubles from baseline after Cosyntropin administration
  • Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration

Treatment

See Also

References