Brugada syndrome

Pathophysiology

Genetically-linked sodium channelopathy, characterized by incomplete RBBB with ST elevation in V1 and V2, and an increased risk of sudden cardiac death

Note - EKG findings can be TRANSIENT

EKG Criteria

• Type 1 - 2 mm J-point elevation a gradually descending ST segment and a negative T-wave
• Type 2 - saddle back pattern with at least 2 mm J-point elevation and at least 1 mm ST elevation with a positive or biphasic T-wave
• Type 3 - saddle back pattern with less than 2 mm J-point elevation and less than 1 mm ST elevation with a positive T-wave

Disposition

• a/w polymorphic v tach, v fib.
• mortality ~10% / yr
• pts need an AICD

Source

Adapted from ....Mattu (lecture)