Lactic acidosis

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Background

  • Most common cause of metabolic acidosis in hospitalized patients
  • Type A
    • Impaired tissue oxygenation
      • Hypovolemia
      • Cardiac failure
      • Sepsis
  • Type B
    • No impaired tissue oxygenation
      • Alcoholism
        • Lactate utilization is impaired 2/2 impaired hepatic gluconeogenesis
      • Metformin
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