Clonidine toxicity

Revision as of 22:38, 28 January 2012 by Jswartz (talk | contribs) (Created page with "==Background== *Alpha-2 and opioid receptor agonist ==Clinical Features== *Cardiac **Bradycardia **Hypotension *Neuro **Lethargy (may progress to apnea) **Miotic pupils ==Treat...")
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Background

  • Alpha-2 and opioid receptor agonist

Clinical Features

  • Cardiac
    • Bradycardia
    • Hypotension
  • Neuro
    • Lethargy (may progress to apnea)
    • Miotic pupils

Treatment

  • Respiratory/neuro depression
    • Naloxone
      • High dose may be required (up to 10mg)
      • Not always effective
  • Bradycardia
    • Atropine
  • Hypotension
    • IVF

Source

  • Tintinalli
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