Template:Peritonitis Antibiotics

	Harbor	Santa Monica	Other
Primary	Ceftriaxone 1g IV once daily OR Ciprofloxacin 400mg IV q12hrs OR Cefazolin 1g (30mg/kg) IV q8hrs OR Levofloxacin 750mg IV once daily + Metronidazole 500mg IV q8hrs	piperacillin/tazobactam 4.5g IV q6h OR ertapenem 1g IV q24h OR ceftriaxone 1g IV q24h +metronidazole 500mg IV q8h vancomycin 15mg/kg/dose IV q12h (Max dose = 1500mg)	Piperacillin-tazobactam OR ticarcillin-clavulanate 3.1 g IV every 6 hours OR ertapenem 1 g every 24 hours OR moxifloxacin 400 mg IV every 24 hours
Allergy or prior exposure	Piperacillin/Tazobactam 4.5g (80mg/kg) IV q8hrs OR Metronidazole 500mg IV q8hrs *Cefepime 2g IV once daily OR Ciprofloxacin 400mg IV q12hrs OR Levofloxacin 750mg IV once daily Meropenem 1g (20mg/kg) IV q8hrs OR Doripenem 500mg IV q8hrs OR + Aztreonam 2g (30mg/kg) IV q8hrs + Metronidazole 500mg IV q8hrs	aztreonam 2g IV q8h + metronidazole 500mg IV q8h +/- vancomycin 15mg/kg/dose IV q12h (Max dose = 1500mg)

Harbor

Metronidazole 500mg IV q8hrs PLUS
- Ceftriaxone 1g IV once daily OR
- Ciprofloxacin 400mg IV q12hrs OR
- Cefazolin 1g (30mg/kg) IV q8hrs OR
- Levofloxacin 750mg IV once daily

Piperacillin/Tazobactam 4.5g (80mg/kg) IV q8hrs OR
Metronidazole 500mg IV q8hrs PLUS
- Cefepime 2g IV once daily OR
- Ciprofloxacin 400mg IV q12hrs OR
- Levofloxacin 750mg IV once daily
Meropenem 1g (20mg/kg) IV q8hrs OR
Doripenem 500mg IV q8hrs OR
Aztreonam 2g (30mg/kg) IV q8hrs + Metronidazole 500mg IV q8hrs

Piperacillin-tazobactam or ticarcillin-clavulanate, 3.1 g IV every 6 hours; or ertapenem, 1 g every 24 hours; or moxifloxacin, 400 mg IV every 24 hours

Primary therapy
- piperacillin/tazobactam 4.5g IV q6h OR ertapenem 1g IV q24h OR ceftriaxone 1g IV q24h
- AND, metronidazole 500mg IV q8h
- vancomycin 15mg/kg/dose IV q12h [Maximum dose of 1500mg]
If allergy or prior exposure
- aztreonam 2g IV q8h
- AND, metronidazole 500mg IV q8h
- +/- vancomycin 15mg/kg/dose IV q12h [Maximum dose of 1500mg]