Digoxin
Revision as of 21:50, 18 November 2011 by Rossdonaldson1 (talk | contribs)
Adult Dosing
- Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg
Contraindications
- WPW
- Increases conduction velocity in atrial tissue
Indications
- RVR control in a-fib/flutter, PSVT
Mechanism of Action
- Inhibits NaK pump
- Positive inotropy
- Negative chronotropy/dromotropy
- Indirect vagal stimulator
Adverse Drug Rxns
- GI - N/V, diarrhea, abd pain
- CV - Bradycardia, SA/AV block, ventr arrhythmias
Kinetics
Onset of action = 1.5-4hr (IV)