Vasopressin

Revision as of 15:54, 22 March 2016 by Ostermayer (talk | contribs) (Text replacement - "Category:Drugs" to "Category:Pharmacology")

General

Adult Dosing

Dosing

  • 0.04 units/min

Rate of Titration

  • Fixed dose (do not titrate)

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Bradycardia
  • Limb ischemia
  • Myocardial ischemia
  • Splanchnic ischemia

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

Primary Receptor

  • V1

Relative Effects

  • ↑SVR
  • ↓HR

Notes

  • Adverse effects are dose-dependent
  • Acts on V1 receptors leading to ↑vasoconstriction and

↑sensitivity to catecholamines in pts with shock

Indication

  • Adjunct for septic shock

See Also

Sources

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