Mycophenolate mofetil

Administration

• Type: Immunosuppressant
• Dosage Forms: 250,500; 200 mg/mL; IV
• Routes of Administration: PO, IV
• Common Trade Names: CellCept

Adult Dosing

Kidney transplant rejection prophylaxis

• 1 g PO/IV bid
• Start: IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach; stable pts may take w/ food

Heart transplant rejection prophylaxis

• 1.5 g PO/IV bid
• Start: IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach

Liver transplant rejection prophylaxis

• 1.5 g PO bid or 1 g IV bid
• Info: start IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach

Lupus nephritis

• 1 g PO bid
• Info: use w/ prednisone, consider decease dose 50% after 6mo tx

Special Populations

• Pregnancy Rating:
• Lactation risk:

Renal Dosing

• Adult:
• Pediatric:

Hepatic Dosing

• Adult:
• Pediatric:

Contraindications

• Allergy to class/drug

Pharmacology

• Half-life:
• Metabolism:
• Excretion: