Parvovirus B19

Background

• In children: causes erythema infectiousum (Fifth disease)
• In transplant patients on immunosuppressive drugs: causes RBC aplasia.
  • Short-lived, may not be discovered
  • Parvovirus only replicated in erythroid progenitor cells

Clinical Features

• Erythema infectiosum (fifth disease)
• Anemia

References

• Fish RM, Massad MG. The Transplant Patient. In: Tintinalli JE, Stapczynski J, Ma O, Cline DM, Cydulka RK, Meckler GD, T. eds. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. New York, NY: McGraw-Hill; 2011.
• Place R, Lagoc AT, Mayer TA, Lawlor CJ. Oncology and Hematology Emergencies in Children. In: Tintinalli JE, Stapczynski J, Ma O, Cline DM, Cydulka RK, Meckler GD, T. eds. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. New York, NY: McGraw-Hill; 2011