Template:Crofab indications

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The following criteria for administration after Crotalidae bite allows for clinician judgment and shared decision making with the patient due to the extreme cost of Crofab[1]

  1. Progression of swelling
  2. Abnormal results on lab tests (plt < 100,000 or fibrinogen < 100)
  3. Systemic manifestations (unstable vitals or AMS)
  4. Neuromuscular toxicity

No studies show reduction in mortality from antivenom administration.

  1. Lavonas EJ et al: Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop. BMC Emerg Med. 2011; 11.