EBQ:Paramedic Trial

Under Review Journal Club Article

Perkins GD. et al.. "Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial". Lancet. 2015. 385(9972):947-55.
PubMed Full text PDF

Clinical Question

Does prehospital LUCAS-2 mechanical CPR improve survival from out-of-hospital cardiac arrest?

Conclusion

The use of LUCAS-2 in non-traumatic, out-of-hospital cardiac arrests did not show improvement over manual CPR in patient survival to 30 days.

Major Points

Survival to 30 days had no difference with 6% (LUCAS-2) vs. 7% (control)
No difference in ROSC, survival of event, survival to 3 months, or survival to 12 months
Decreased favorable neurologic outcome (CPC 1 or 2) in LUCAS-2 group

Study Design

Pragmatic, cluster randomized, controlled trial

Population

Patient Demographics

Inclusion Criteria

Exclusion Criteria

Interventions

Outcomes

Primary Outcome

Secondary Outcomes

Subgroup analysis

Criticisms & Further Discussion

External Links

Funding

Sources

Authors: