Calcium gluconate

General

• Type:
• Dosage Forms: IV/PO
• Common Trade Names: Calcium Gluconate

Adult Dosing

• Calcium Supplementation
  • 19-50 years old: 1000 mg/day PO (divided q8-12hr)
  • >50 years old: 1200 mg/day PO (divided q8-12hr)
  • Pregnant or breastfeeding patient: 1000 mg/day PO (divided q8-12hr)

Special Populations

• Pregnancy Rating: Class C
• Lactation risk: Use with caution
• Renal Dosing
  • Adult
  • Pediatric
• Hepatic Dosing
  • Adult
  • Pediatric

Contraindications

• Allergy to class/drug

Pharmacology

• Half-life:
• Metabolism:
  • Absorption requires Vitamin D
  • ~45% protein bound (primarily to albumin)
• Excretion: Feces (80%), Urine (20%)
• Mechanism of Action: Bone mineral component; cofactor in enzymatic reactions, essential for neurotrasmission, muscle contraction, and many signal transduction pathways.