Acrylonitrile toxicity

Background

  • Unique type of Cyanide toxicity
  • Used in the production of plastics
    • Structure: Nitrile group linked to a Vinyl group

Mechanism of Action

  • Chemical itself is hepatotoxic
  • Also metabolized to form cyanide molecule

Clinical Features

Differential Diagnosis

Diagnosis

Treatment

References

  • Haddad and Wincester's Toxicology page 1309
  • Wikipedia