Ondansteron

Revision as of 10:10, 13 April 2015 by Dx316gol (talk | contribs) (added page)

General

  • Type: anti-emetic
  • Dosage Forms:4, 8
  • Common Trade Names: Zofran

Adult Dosing

  • Nausea/Vomiting: 4-8 mg q4h, max 24 mg a day

Pediatric Dosing

  • Nausea/Vomiting: 0.1 mg/kg IV q4h max dose at once:4-8 mg, max 24 mg

Special Populations

  • Pregnancy Rating:B
  • Lactation:safety unknown
    • Adult:
  • Renal Dosing:not defined
  • Hepatic Dosing: not defined
    • Pediatric:
  • Hepatic Dosing: not defined
  • Renal Dosing:not defined

Contraindications

  • Allergy to class/drug
  • congenital long QT syndrome

Adverse Reactions

Serious

  • bronchospasm
  • steven-johnson syndrome
  • QT prolongation
  • torsades de pointes
  • serotonin syndrome
  • extrapyramidal SX
  • blindness, transient

Common

  • headache
  • constipation
  • fatigue
  • hypoxia
  • fever
  • urinary retention
  • agitation

Pharmacology

  • Half-life: 4.6-5.7 hour
  • Metabolism: liver
  • Excretion: urine
  • Mechanism of Action:selectively antagonizes serotonin 5-HT3 receptors

See Also

Sources

Retrieved from "https://www.wikem.org/w/index.php?title=Ondansteron&oldid=35899"