Lisinopril

Revision as of 02:21, 1 April 2015 by Dx316gol (talk | contribs) (special population)

General

  • Type: ACE inhibitor
  • Dosage Forms: 2.5, 5, 10, 20, 30, 40
  • Common Trade Names: Prinivil, Zestril

General information: doses > 40 mg/day rarely more effective, decreased efficacy as mono therapy in african-american patients

Adult Dosing

  • HTN: 10 - 40 mg PO Qday, max 80 mg/day

Pediatric Dosing

  • 6-16 year old: 0.07 mg/kg PO qday, max 40 mg/day

Special Populations

  • Pregnancy Rating: D
  • Lactation: Safety unknown
  • Renal Dosing
    • Adult: CrCl < 30, start 2.5 mg qday, max 40 mg q/day
    • Pediatric Cr Cl 30-50: decrease dose 50%, CrCl < 30, avoid use
  • Hepatic Dosing
    • Adult: Not defined
    • Pediatric: Not defined

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Sources

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