Dalbavancin

Administration

• Type: Antibiotic
• Dosage Forms: 500 mg/vial; reconstituted concentration 20 mg/ml
• Routes of Administration: Intravenous
• Common Trade Names: Dalvance

Adult Dosing

• 1500 mg as single dose or 1000 mg then 500 mg one week later; infuse over 30 minutes

Pediatric Dosing

• Safety and efficacy not established in pediatric patients

Special Populations

Pregnancy Rating

• Maternal risk cannot be ruled out

Lactation risk

• Fetal risk cannot be ruled out

Renal Dosing

• Adult:
• Pediatric:

Hepatic Dosing

• Adult:
• Pediatric:

Contraindications

• Allergy to class/drug

Adverse Reactions

Serious

• Gastrointestinal: Clostridium difficile colitis (<2%), Clostridium difficile diarrhea, GI bleed (<2% )

•Hepatic: ALT/SGPT level raised (0.8%) •Immunologic: Hypersensitivity reaction

Common

•Gastrointestinal: Diarrhea (Up to 4.4%), Nausea (Up to 5.5%) •Neurologic: Headache (Up to 4.7%)

Pharmacology

• Half-life:
• Metabolism:
• Excretion: