Contrast with Renal Dysfunction

Indication

Indication = Cr > 1.1

Harbor Cut-off 1.5 for CT

PreTreatment

Most give mucomyst, although in the original study patients received mucomyst much before the CT

Mucomyst

Mucomyst 600mg PO

Bicarb Drip=

  • 3 amps NaBicarb in 1L of D5H2O
    • Bolus 3mL/kg 1hr prior to IV contrast,
    • then 1mL/kg/hr for 6hrs after

Source

Merten et al, JAMA 2004