EBQ:Antibiotic prophylaxis for mammalian bites

Revision as of 19:18, 3 November 2014 by Cchoff (talk | contribs) (EBQ)
incomplete Journal Club Article
Medeiros I., Saconato H.. "Antibiotic prophylaxis for mammalian bites". Cochrane Database Syst Rev. 2001. 2(CD001738):.
PubMed Full text PDF

Clinical Question

Is the use of prophylactic antibiotics for mammalian bites effective in preventing wound infections?

Conclusion

Antibiotic prophylaxis after human bites and bites of the hand may decrease the risk of wound infection but further evidence is needed. No evidence shows effectiveness in the use of antibiotic prophylaxis after cat or dog bites.

Major Points

Study Design

  • Systematic review of randomized and quasi-randomized controlled trials
  • Studies were reviewed by two reviewers
  • 8 studies included

Population

Patient Demographics

Inclusion Criteria

  • RCT's included which studied patient's with mammalian bites
    • Compared abx vs. placebo OR no intervention
    • Ability to determine infection at bite site
  • Patients who present for medical care within 24 hours of bite AND no signs of infection

Exclusion Criteria

Interventions

Outcomes

Primary Outcome

Secondary Outcomes

Subgroup analysis

Criticisms & Further Discussion

Funding

Sources

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