Malignant bone tumors
Revision as of 23:05, 21 November 2019 by Mtjordan91 (talk | contribs) (→Differential DiagnosisNiederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.)
Background
Clinical Features
Differential Diagnosis[1]
| Name | Presentation | Radiograph Findings | Clinical Importance |
| Adamantinoma | Bone pain over anterior tibia in adolescent or young adult | Soap Bubble osteolytic appearance on plain radiograph | "Metastasis to lungs |
| May need amputation" | |||
| Chordoma | "Constant pain if in sacrum | ||
| Neurological deficits if at base of skull, most commonly in cranial nerves to the eye " | Plain radiograph will show a destructive bone lesion often with an associated soft tissue mass | "Slow growing but locally aggressive | |
| Metastasis is uncommon, local recurrence is much more likely" | |||
| Fibrosarcoma and Undifferentiated pleomorphic sarcoma | Similar to osteosarcoma except malignant fibroblasts but less common | Most common in distal femur and proximal tibia | Similar outcome to osteosarcoma |
| Primary bone lymphoma | Adult > 40 years of age with bone pain or pathologic fracture | "Bone destruction | |
| Soft tissue mass" | 5 year survival is greater than 50% with radiation and chemotherapy |
Evaluation
Management
Disposition
References
- ↑ Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.