Malignant bone tumors
Revision as of 22:57, 21 November 2019 by Mtjordan91 (talk | contribs) (Created page with "==Background== ==Clinical Features== ==Differential Diagnosis<ref>Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences...")
Background
Clinical Features
Differential Diagnosis[1]
| Name | Presentation | Radiograph Findings | Clinical Importance |
| Adamantinoma | Bone pain over anterior tibia in adolescent or young adult | Soap Bubble osteolytic appearance on plain radiograph | Metastasis to lungs |
| May need amputation | |||
| Chordoma | Constant pain if in sacrum | Plain radiograph will show a destructive bone lesion often with an associated soft tissue mass | Slow growing but locally aggressive |
| Neurological deficits if at base of skull, most commonly in cranial nerves to the eye | Metastasis is uncommon, local recurrence is much more likely | ||
| Fibrosarcoma and Undifferentiated pleomorphic sarcoma | Similar to osteosarcoma except malignant fibroblasts but less common | Most common in distal femur and proximal tibia | Similar outcome to osteosarcoma |
| Primary bone lymphoma | Adult > 40 years of age with bone pain or pathologic fracture | Bone destruction | 5 year survival is greater than 50% with radiation and chemotherapy |
| Soft tissue mass |
Evaluation
Management
Disposition
References
- ↑ Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.