Osteosarcoma

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Background

  • Most common primary pediatric bone tumor; 3% of all childhood cancers
  • Around two-thirds of those diagnosed with non-metastatic disease under the age of 40 will be long-term survivors or cured of the disease with appropriate treatment
  • Survival is less than 20 percent with metastatic disease
  • Bimodal as it peaks in early adolescence and over the age of 65

Pathophysiology

  • Overproduction of osteoid and immature bone by malignant osteoblasts


Clinical Features

Differential Diagnosis

Evaluation

Management

Disposition

See Also

External Links

References