Piperacillin/Tazobactam

General

• Type: Anti-Pseudomonal Penicillin
• Dosage Forms:
• Common Trade Names: Zosyn

Adult Dosing

General

• 3.375 g IV q6 hours
• Alt: 4.5 g q6-8 hours
• Max: 18 g/day

Diverticulitis

• 3.375 g IV q6 hours x 7-10 days

Pneumonia

• CAP
  • 3.375 g IV q6 hours x 7-10 days
  • Only for P. aeruginosa caused or from aspiration
• Nosocomial
  • 4.5 g IV q6 hours x 7-14 days
  • + aminoglycoside or antipseudomonal fluoroquinolone

Special Populations

• Pregnancy:
• Lactation:
• Renal Dosing
  • Adult
  • Pediatric
• Hepatic Dosing
  • Adult
  • Pediatric

Contraindications

• Allergy to class/drug

Pharmacology

• Half-life:
• Metabolism:
• Excretion:
• Mechanism of Action:

See Also

• Antibiotics (Main)