Community-Associated Methicillin-Resistant Staphylococcus Aureus (CA-MRSA)

Background

Organisms	'	Staph. aureus (CA-MRSA)
Penicillins	Penicillin G	0
	Penicillin V	0
Anti-Staphylocccal Penicillins	Methicillin	0
	Nafcillin/Oxacillin	0
	Cloxacillin/Diclox.	0
Amino-Penicillins	AMP/Amox	0
	Amox/Clav	0
	AMP-Sulb	0
Anti-Pseudomonal Penicillins	Ticarcillin	0
	Ticar-Clav	0
	Pip-Taxo	0
Carbapenems	Piperacillin	0
	Doripenem	0
	Ertapenem	0
	Imipenem	0
	Meropenem	0
	Aztreonam	0
Fluroquinolones	Ciprofloxacin	+/-
	Ofloxacin
	Pefloxacin
	Levofloxacin	+/-
	Moxifloxacin	+/-
	Gemifloxacin	+/-
	Gatifloxacin	+/-
1st G Cephalosporin	Cefazolin	0
2nd G. Cephalosporin	Cefotetan	0
	Cefoxitin	0
	Cefuroxime	0
3rd/4th G. Cephalosporin	CefoTAXime	0
	Cefizoxime	0
	CefTRIAXone	0
	Ceftobiprole	+
	Ceftaroline	+
	CefTAZidime	0
	Cefepime	0
Oral 1st G. Cephalosporin	Cefadroxil	0
	Cephalexin	0
Oral 2nd G. Cephalosporin	Cefaclor/Loracarbef	0
	Cefproxil	0
	Cefuroxime axetil	0
Oral 3rd G. Cephalosporin	Cefixime	0
	Ceftibuten	0
	Cefpodox/Cefdinir/Cefditoren	0
Aminoglycosides	Gentamicin
	Tobramycin
	Amikacin
	Chloramphenicol
	Clindamycin	+/-
Macrolides	Erythromycin	+/-
	Azithromycin	+/-
	Clarithromycin	+/-
Ketolide	Telithromycin	+/-
Tetracyclines	Doxycycline	+
	Minocycline	+
Glycylcycline	Tigecycline	+
Glyco/Lipoclycopeptides	Vancomycin	+
	Teicoplanin	+
	Telavancin	+
	Fusidic Acid	+
	Trimethoprim	+
	TMP-SMX	+
Urinary Agents	Nitrofurantoin	+
	Fosfomycin
Other	Rifampin	+
	Metronidazole	0
	Quinupristin dalfoppristin	+
	Linezolid	+
	Daptomycin	+
	Colistimethate	0

S susceptible/sensitive (usually)
I intermediate (variably susceptible/resistant)
R resistant (or not effective clinically)
S+ synergistic with cell wall antibiotics
U sensitive for UTI only (non systemic infection)
X1 no data
X2 active in vitro, but not used clinically
X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
X4 active in vitro, but not clinically effective for strep pneumonia

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