Cefazolin
General
- Type: 1st gen Cephalosporin
- Dosage Forms: IV, IM
- Common Trade Names: Ancef
Adult Dosing
General
- Mild: 250-500 mg IM/IV 8h
- Mod-Severe: 500-1000 mg IM/IV q6-8h
- Life Threatening: 1-1.5g IM/IV q6h
- Max: 12g/day
UTI, Uncomplicated
- 1g IM/IV q12
Pneumococcal Pneumonia
- 500mg IM/IV q12
Endocarditis Prophylaxis, Dental
- 1g IM/IV x1 (30-60 min before procedure)
Pediatric Dosing
Special Populations
- Pregnancy: B
- Lactation: Safe
- Renal
- Hepatic
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: 1.8h (3.7 ESRD)
- Metabolism: other; CYP450
- Excretion: Urine
- Mechanism of Action: Bactericidal; inhibits cell wall mucopeptide synthesis
See Also
Source
- Epocrates