Fresh frozen plasma

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Features

  1. Contains all coagulation factors and fibrinogen
    1. 40 mL/kg raises any factor by 100% (each unit is ~200mL)
  2. May cause fluid overload
  3. ABO compatibilty a must but crossmatch before transfusing not
  4. INR of FFP is ~1.2

Indications

  1. Rapid reversal of warfarin over-anticoagulation
  2. Bleeding and multiple coagulation defects
  3. Correction of coagulation defects for which no specific factor is available
  4. Transfusion of more than one blood volume w/ evidence of active bleeding + coagulopathy

Dose

  1. Transfuse at least 15 mL/kg at a time (4 units in 70-kg adult)

See Also

Source

Tintinalli