Template:HIV post-exposure prophylaxis regimens

2 drug Basic[1]

  • Tenofovir-emtricitabine (Truvada) one tablet (300 mg of tenofovir with 200 mg of emtricitabine) once daily OR
  • Zidovudine–lamivudine (Combivir) one tablet (300 mg of zidovudine with 150 mg of lamivudine) twice daily
    • this regimen is preferred in pregancy

3 drug Expanded[1]

  • Ritonavir–lopinavir (Kaletra) PLUS either tenofovir–emtricitabine or zidovudine–lamivudine)
    • Two tablets (50 mg of ritonavir with 200 mg of lopinavir per tablet) twice daily, or four tablets once daily
  • Ritonavir plus atazanavir (plus either tenofovir–emtricitabine or zidovudine–lamivudine
    • 100 mg of ritonavir plus 300 mg of atazanavir once daily
  • Ritonavir plus darunavir (plus either tenofovir–emtricitabine or zidovudine–lamivudine)
    • 100 mg of ritonavir plus two tablets, each containing 400 mg of darunavir, once daily
  1. 1.0 1.1 Landovitz RJ, Currier JS. Postexposure prophylaxis for HIV infection. N Eng J Med. 2009 Oct 29; 361(18): 1768-75. PDF