Anemia

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Treatment

Hb <6 --> almost always transfuse

Hb >10 --> almost never transfuse

DDX

  1. Hemorrhage
  2. Destruction (hemolytic)
    1. Hereditary
    2. Acquired
  3. Impaired Production
    1. Hypochromic (microcytic)
      1. Fe deff, chronic disease, thalassemias, sideroblastic
    2. Aplastic/myelodysplastic (normocytic)
      1. marrow failure, chemicals (ETOH), radiation, infection (HIV, parvo), RF
    3. Megaloblastic (macrocytic)
      1. vit B12/folate def, drugs (chemo), HIV

Source

1/26/06 DONALDSON (adapted from Tintinalli's)

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