Template:Thrombocytopenia

Thrombocytopenia

• Decreased production
  • Marrow infiltration (tumor or infection)
  • Viral infections (rubella, HIV)
  • Drugs
    • Heparin-Induced Thrombocytopenia (HIT)
    • sulfa antibiotics, ETOH, ASA, thiazides/furosemide
  • Radiation
  • Vitamin B12 and/or folate deficiency
• Increased platelet destruction
  • Idiopathic thrombocytopenic purpura
  • Thrombotic Thrombocytopenic Purpura (TTP)
  • Hemolytic Uremic Syndrome (HUS)
  • Disseminated Intravascular Coagulation (DIC)
  • Viral infections (HIV, mumps, varicella, EBV)
  • Drugs (heparin, protamine)
• Platelet loss
  • Excessive hemorrhage
  • Hemodialysis, extracorporeal circulation
• Splenic sequestration
  • Sickle cell disease, cirrhosis