Template:Vasopressor table

Vasopressors

Pressor	Initial Dose	Max Dose	Cardiac Effect	BP Effect	Arrhythmias	Special Notes
Dobutamine	2.5mcg/kg/min	10-40 mcg/kg/min	mainly inotrope (ß1)	alpha effect minimal	Some HR(ß1) increase. Also Increase SA and AV node fx	Debut Research 1979 Isoproterenol has most Β2 vasodilatory and Β1 HR effects
Dopamine	2mcg/kg/min	20-50 mcg/kg/min	β1 and NorEpi release	α effects if > 20mcg/kg/min	Arrhythmogenic from β1 effects	More adverse events when used in shock compared to Norepi
Epinepherine	0.1-1 mcg/kg/min
Norepinephrine	8-12mcg/min	30 mcg/min	β1 direct effect	β1 and α1,2 effects	Less arrhythmias than Dopamine	Increases MAP, coronary perfusion pressure, little β2 effects.
Milrinone	50mcg/kg x 10 min	0.375-75mcg/kg/min	Direct influx of Ca2+ channels	Smooth muscle vasodilator		PDE Inhibitor which increases Ca2+ uptake by sarcolemma. No venodilatory activity
Phenylephrine	100-180mcg/min then 40-60mcg/min	0.4-9 mcg/kg/min		Alpha agonist		Long half life
Vasopressin	Fixed Dose	0.4 U/min	unknown	increases via ADH peptide		should not be titrated due to ischemic effects

Medication	IV Dose (mcg/kg/min)	Concentration
Norepinephrine (Levophed)	0.1-2 mcg/kg/min	8mg in 500mL D5W
Dopamine	2-20 mcg/kg/min	400mg in 250 D5W
Dobutamine	2-20 mcg/kg/min	250mg in 250 mg D5W
Epinephrine	0.1-1 mcg/kg/min	1mg in 250 D5W