CMV colitis
Background
- CMV is part of the Herpesviridae family
- 50-80% of the world's population is seropositive for CMV
- Causes a mild or undetectable infection in immunocompetent hosts
- Severe systemic illness is found in immunosuppressed hosts
Clinical Presentation
Differential Diagnosis
- Bacterial Gastroenteritis
- Campylobacter Infections
- Clostridium Difficile Colitis
- Colon Cancer
- Crohn Disease
- Cryptosporidiosis
- Mycobacterium Avium-Intracellulare
- Toxic Megacolon
- Ulcerative Colitis
- Viral Gastroenteritis
Diagnosis
Management
Disposition
- Ganciclovir 5mg/kg IV q12hrs x 21 days
- Foscarnet 90mg/kg IV q12hrs x 21 days