Necrotizing enterocolitis

Background

  • usu 24-48 hr of life/neonates & premature infants
  • It is d/t intestinal wall necrosis

Diagnosis

  • S/S: feeding intolerance, jaundice, abdominal distension, change in stooling pattern, heme + stools
  • radiology= pneumotosis intestinalis, pneumobilia, pneumoperitoneum, air in portal vein, gasless abdomen

Signs of functional Intestinal obstruction : Abdominal distension, progressive decreased Peristalsis, Bilious vomiting, hematemesis and blood in stools

Signs of peritonitis & perforation: Ascites, erythema & edema of abdominal wall, localized mass or rigidity

Systemic signs : respiratory distress, Apnea / bradycardia, Lethargy, thermal instability, irritability, poor feeding, hypotension (shock), oliguria, bleeding diathesis, sclerema

Triad of

  1. Thrombocytopenia
  2. Metabolic acidosis
  3. Hyponatremia

Clinical triad

  1. Distension
  2. GI bleeding
  3. Pneumatosis intestinalis

Stools are heme +


Radiography

  • Pneumotosis is hallmark
    • Get KUB and left lat decubital

DDx

  1. Sepsis
  2. pneumonia
  3. malro/volvulus
  4. intuss
  5. feeding intolerance (exclusion)

Treatment

  1. NPO
  2. CBC, lytes, BCx, x-ray
  3. Amp/gent/clinda x 48 hrs
  4. Serial CBC, lytes, x-ray (q6)
  5. NG to suction
  6. Volume replacement

Surgery Indications

  1. Perforation
  2. portal/biliary air
  3. rapidly deteriorating

Prognosis

  • Rx= 80% nd only medical mgt (bowel rest, ngt, fluids, abx to cover bowel flora), 20% need bowel surgery (if perf etc)
  • 15% mortality

Source

Adapted from Pani