Warfarin
Revision as of 06:23, 4 July 2011 by Rossdonaldson1 (talk | contribs)
Dosing
- Day 1: 5 to 7.5 mg po at night (to ensure absorption on an empty stomach),
- Day 2, 3, 4...: 2.5 to 7.5 mg po qhs (most often 5 mg)
- An increase in INR of >0.3-0.4 units per day necessitates dose reduction
- CHF, liver disease, Vitamin K def, drugs may influence warfarin response
Range (INR)
2.5 to 3.5: mechanical prosthetic valves or recurrent thromboembolism
2.0-3.0: all other indications
Reversal
Source
1/26/06 DONALDSON (addapted from Lampe), EMP 1/11