Etomidate

RSI

0.3 mg/kg bolus IV {Adult standard = 20mg)

Procedural Sedation

0.15 mg/kg bolus IV (Adult standard = 10mg)

Controversy

"The available evidence suggests that etomidate suppresses adrenal function transiently without demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality."

Source

  1. Hohl CM, Kelly-Smith CH,Yeung TC, Sweet DD, Doyle-Waters MM, Schulzer M. The effect of a bolus dose of Etomidate on cortisol levels, mortality, and health services utilization: a systematic review. Ann Emerg Med. 2010;56(2):105-113.

See Also