Digoxin: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
== Adult Dosing ==
== Adult Dosing ==
*Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg
*Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg)


== Contraindications ==
== Contraindications ==
Line 15: Line 15:
**Indirect vagal stimulator
**Indirect vagal stimulator


== Adverse Drug Rxns ==
== Adverse Drug Reactions==
*GI - N/V, diarrhea, abd pain
*GI: N/V, diarrhea, abd pain
*CV - Bradycardia, SA/AV block, ventr arrhythmias
*CV: Bradycardia, SA/AV block, ventr arrhythmias


== Kinetics ==
== Kinetics ==
Onset of action = 1.5-4hr (IV)
*Onset of action = 1.5-4hr (IV)


==See Also==
==See Also==

Revision as of 17:33, 27 May 2012

Adult Dosing

  • Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg)

Contraindications

  • WPW
    • Increases conduction velocity in atrial tissue

Indications

  • RVR control in a-fib/flutter, PSVT

Mechanism of Action

  • Inhibits NaK pump
    • Positive inotropy
  • Negative chronotropy/dromotropy
    • Indirect vagal stimulator

Adverse Drug Reactions

  • GI: N/V, diarrhea, abd pain
  • CV: Bradycardia, SA/AV block, ventr arrhythmias

Kinetics

  • Onset of action = 1.5-4hr (IV)

See Also