Iodoquinol: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
* | *650mg 3 times daily after meals for 20 days | ||
**Not to exceed 1.95 g daily | **Not to exceed 1.95 g daily | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*Children: 30- | *Children: 30-40mg/kg daily (maximum: 650mg per dose) in 3 divided doses for 20 days | ||
**Not to exceed 1.95 g daily | **Not to exceed 1.95 g daily | ||
Revision as of 11:24, 20 July 2016
Administration
- Type: Amebicide
- Routes of Administration: Oral
- Common Trade Names: Aloquin; Yodoxin
Adult Dosing
- 650mg 3 times daily after meals for 20 days
- Not to exceed 1.95 g daily
Pediatric Dosing
- Children: 30-40mg/kg daily (maximum: 650mg per dose) in 3 divided doses for 20 days
- Not to exceed 1.95 g daily
Special Populations
- Limited data on use during pregnancy
Renal Dosing
- No adjustments noted by manufacturer
Hepatic Dosing
- No adjustments noted by manufacturer
Contraindications
- Allergy to class/drug
- Concerns with optic neuritis
- Concerns with peripheral neuropathy
Adverse Reactions
- Nausea/vomiting
- Chills
- Fever
- Headache, vertigo
- Pruritus
- Thyroid gland enlargement
- Abdominal cramps
- Peripheral neuropathy
- Optic atrophy
- Optic neuritis
Pharmacology
- Half-life:
- Metabolism: Liver
- Excretion: Feces, urine
Mechanism of Action
It is a contact amebicide that works in the lumen of the intestine (unknown mechanism)
Comments
See Also
References
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