ACTH (cosyntropin) stimulation test: Difference between revisions
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#Time 60: Draw serum cortisol & give 100mg hydrodortison IVP | #Time 60: Draw serum cortisol & give 100mg hydrodortison IVP | ||
^0.125mg if <2yrs old | ^0.125mg if <2yrs old | ||
Normal Response: Cortisol level doubles from baseline after Cosyntropin administration | Normal Response: Cortisol level doubles from baseline after Cosyntropin administration | ||
Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration | Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration | ||
Revision as of 08:52, 28 February 2012
Cosyntropin
- Before: Draw serum cortisol
- Time 0: ^0.25mg IM/IV over 2min
- Time 30: Draw serum cortisol
- Time 60: Draw serum cortisol & give 100mg hydrodortison IVP
^0.125mg if <2yrs old
Normal Response: Cortisol level doubles from baseline after Cosyntropin administration Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration
Treatment
- Then give either
- dexamethasone 6mg IV
- OR
- Hydrocortisone 100mg IV
Source
2/22/06 DONALDSON (from Pharmacopoeia) Emedicine Adrenal Crisis in Emergency Medicine