Atropine: Difference between revisions

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==Adult Dosing ==
==Adult Dosing==
*Loading dose = 0.5mg rapid IV bolus q3-5min (max = 0.04 milligram/kg)
*Loading dose = 0.5mg rapid IV bolus q3-5min (max = 0.04 milligram/kg)
*May be given IM, IO, SC
*May be given IM, IO, SC


==Indications ==
==Indications==
*Symptomatic sinus or AV nodal bradycardia
*Symptomatic sinus or AV nodal bradycardia


==Mechanism of Action ==
==Mechanism of Action==
*Parasympatholytic
*Parasympatholytic
**Increases sinus/AV conduction
**Increases sinus/AV conduction


==Adverse Drug Reactionss ==
==Adverse Drug Reactionss==
*Increased O2 consumption
*Increased O2 consumption
*If given slowly (or <0.5mg) may lead to paradoxical bradycardia
*If given slowly (or <0.5mg) may lead to paradoxical bradycardia


==Kinetics ==
==Kinetics==
*Onset of action = 2-4min
*Onset of action = 2-4min
*Duration of action = 5hr
*Duration of action = 5hr

Revision as of 23:16, 5 July 2016

Adult Dosing

  • Loading dose = 0.5mg rapid IV bolus q3-5min (max = 0.04 milligram/kg)
  • May be given IM, IO, SC

Indications

  • Symptomatic sinus or AV nodal bradycardia

Mechanism of Action

  • Parasympatholytic
    • Increases sinus/AV conduction

Adverse Drug Reactionss

  • Increased O2 consumption
  • If given slowly (or <0.5mg) may lead to paradoxical bradycardia

Kinetics

  • Onset of action = 2-4min
  • Duration of action = 5hr

See Also