Stevens-Johnson syndrome and toxic epidermal necrolysis: Difference between revisions
(Created page with "==Background== *SJS and TEN involve IC-mediated cell death w/ separation of epidermis from dermis **SJS involves <10% of BSA **TEN involves >30% of BSA ==Diagnosis== *Often have...") |
No edit summary |
||
| Line 6: | Line 6: | ||
==Diagnosis== | ==Diagnosis== | ||
*Often have prodrome (fever, URI symptoms, HA, malaise) | *Often have prodrome (fever, URI symptoms, HA, malaise) | ||
*Rash begins suddenly | *Rash begins suddenly | ||
**Target | **Target lesions | ||
*Mucous membranes can be severely affected | |||
**Eye involvement can be severe | **Eye involvement can be severe | ||
*In severe cases, respiratory tract and GI involvement may occur | |||
==Work-Up== | ==Work-Up== | ||
Revision as of 19:39, 2 February 2012
Background
- SJS and TEN involve IC-mediated cell death w/ separation of epidermis from dermis
- SJS involves <10% of BSA
- TEN involves >30% of BSA
Diagnosis
- Often have prodrome (fever, URI symptoms, HA, malaise)
- Rash begins suddenly
- Target lesions
- Mucous membranes can be severely affected
- Eye involvement can be severe
- In severe cases, respiratory tract and GI involvement may occur
Work-Up
Treatment
- Removal of inciting cause if identified
- Treat shock w/ IV fluids according to burn protocols
Disposition
- Admit to burn unit or ICU
Source
Tintinalli