Hydrocortisone topical: Difference between revisions
Ostermayer (talk | contribs) (Text replacement - "Category:Drugs" to "Category:Pharmacology") |
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*Allergy to class/drug | *Allergy to class/drug | ||
*caution if skin infection | *caution if skin infection | ||
*caution in pediatric | *caution in pediatric patients | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
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*Cushing syndrome | *Cushing syndrome | ||
*hyperglycemia | *hyperglycemia | ||
*intracranial HTN (peds | *intracranial HTN (peds patients) | ||
===Common=== | ===Common=== | ||
Revision as of 16:50, 21 June 2016
General
- Type: Topical steroid
- Dosage Forms: 0.5%, 1%, 2.5% crm, lotion, oint
- Common Trade Names: Cortizone, Cortaid, Hytone, Texacort
Adult Dosing
Dermatoses, steroid-responsive
- Apply bid-qid
Pediatric Dosing
Dermatoses, steroid-responsive
- Apply bid-qid
Special Populations
- Pregnancy Rating: C
- Lactation: Excretion in milk unknown; use with caution
- Renal Dosing: None
- Hepatic Dosing: None
Contraindications
- Allergy to class/drug
- caution if skin infection
- caution in pediatric patients
Adverse Reactions
Serious
- HPA axis suppresion
- Cushing syndrome
- hyperglycemia
- intracranial HTN (peds patients)
Common
- burning
- pruritus
- irritation
- dryness
- folliculitis
- hypertrichosis
- acneiform dermatitis
- hypopigmentation
- perioral dermatitis
- allergic contact dermatitis
- maceration
- secondary infection
- skin atrophy
- striae
- miliaria
Pharmacology
- Half-life: 8-12h
- Metabolism: liver primarily; CYP450
- Excretion: urine
- Mechanism of Action: exact mechanim of anti-inflammatory action unknown; inhibits multiple inflammatory cytokines; produces multiple gluocorticoid and mineralocorticoid effects