EM Podcasts: Difference between revisions
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Revision as of 01:31, 10 January 2012
Overview table
| Class | Known as | Examples | Mechanism | Clinical uses |
|---|---|---|---|---|
| Ia | fast-channel blockers-Affect QRS complex |
|
(Na+) channel block (intermediate association/dissociation) |
|
| Ib- Do not affect QRS complex |
|
(Na+) channel block (fast association/dissociation) |
| |
| Ic |
|
(Na+) channel block (slow association/dissociation) |
| |
| II | Beta-blockers |
|
beta blocking Propranolol also shows some class I action |
|
| III |
|
K+ channel blocker Sotalol is also a beta blocker Amiodarone has Class I, II, and III activity |
| |
| IV | slow-channel blockers |
|
Ca2+ channel blocker |
|
| V |
|
Work by other or unknown mechanisms (Direct nodal inhibition). |
Used in supraventricular arrhythmias, Or in the case of Magnesium Sulfate, used in Torsade de Pointe. |
Source
UpToDate
Katzung & Trevor's Pharmacology
