Glucagon: Difference between revisions
| Line 12: | Line 12: | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
===[[Pediatric hypogylcemia|Hypoglycemia]]=== | ===[[Pediatric hypogylcemia|Hypoglycemia]]=== | ||
*0.03 mg/kg IM/SQ/IV (max = 1 mg) | *0.03 mg/kg IM/SQ/IV x 1 (max = 1 mg) | ||
*Alternative | *Alternative | ||
**'''<20kg''': 0.5mg SC/IM/IV x 1 | **'''<20kg''': 0.5mg SC/IM/IV x 1 | ||
Revision as of 02:13, 9 May 2016
General
- Type:
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Beta-blocker toxicity[1] [2]
- 5mg IV bolus over one minute
- Rebolus if no response after 10min
- If effective, start infusion at 2-5mg/hr
Pediatric Dosing
Hypoglycemia
- 0.03 mg/kg IM/SQ/IV x 1 (max = 1 mg)
- Alternative
- <20kg: 0.5mg SC/IM/IV x 1
- >20kg: 1mg SC/IM/IV x 1
- May repeat q20 min
Beta-blocker toxicity [1] [2]
- Ped: 50mcg/kg
- Rebolus if no response after 10min
- If effective, start infusion at 70mcg/kg/hr
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: 20 minutes
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Sources
- ↑ 1.0 1.1 Kerns W. Management of beta-adrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am. 2007;25(2):309-331. (Review)
- ↑ 2.0 2.1 Bailey B (2003). Glucagon in beta-blocker and calcium channel blocker overdoses: a systematic review. Journal of toxicology. Clinical toxicology, 41 (5), 595-602 PMID: 14514004