Transient ischemic attack: Difference between revisions

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== Definition ==
==Background==
 
*Definition: Transient episode of neurologic dysfunction caused by focal brain, spinal cord, or retinal ischemia without infarction
"Transient episode of neurological dysfunction caused by focal brain, spinal cord, or retinal ischemia without infarction.” Stroke 2009;40[6]:2276


== Background ==
== Background ==
#Ischemic
#Ischemic
##Thrombosis
##Thrombosis
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== Work-Up ==
== Work-Up ==
#[[Head CT]]
#[[Head CT]]
#Labs
#Labs
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== Treatment ==
== Treatment ==
#Head of bed lowered
#Head of bed lowered
#Permissive hypertension
#Permissive hypertension
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== Disposition ==
== Disposition ==
===AHA/ASA Guidelines===
===AHA/ASA Guidelines===
Reasonable to hospitalize patients with TIA who present w/in 72 hr of symptom onset and meet any of the following criteria:
Reasonable to hospitalize patients with TIA who present w/in 72 hr of symptom onset and meet any of the following criteria:
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== Source ==
== Source ==
DONALDSON (Smith, Lampe, NEJM '07, Pani)
*Stroke 2009;40[6]:2276


[[Category:Neuro]]
[[Category:Neuro]]

Revision as of 06:49, 28 September 2011

Background

  • Definition: Transient episode of neurologic dysfunction caused by focal brain, spinal cord, or retinal ischemia without infarction

Background

  1. Ischemic
    1. Thrombosis
    2. Vasculitis
    3. Dissection
  2. Embolic
    1. Cardiac
    2. Carotids
  3. Vasospasm
  4. Hypotension (watershed)

DDx

  1. Hypoglycemia
  2. Infectious endocarditis
  3. Complex Migraine
  4. Peripheral cranial nerve lesions
  5. Seizure

Work-Up

  1. Head CT
  2. Labs
    1. CBC (thrombocytosis)
    2. Chemistry (hyponatremia)
    3. Coags
  3. ECG (a-fib)
  4. CXR
  5.  ?MRI/MRA or ?Neuro labs (ESR?, lipids?)

Treatment

  1. Head of bed lowered
  2. Permissive hypertension
  3. NS 500cc bolus, then 150cc/hr (non-CHF/fluid overloaded)
  4. ASA
  5. Heparin if cardiac embolic source/a-fib (usually different vascular territories)

Disposition

AHA/ASA Guidelines

Reasonable to hospitalize patients with TIA who present w/in 72 hr of symptom onset and meet any of the following criteria:

  1. ABCD2 score of ≥ 3
  2. ABCD2 score of 0-2 and uncertainty that the diagnostic workup can be completed within two days as an outpatient
  3. ABCD2 score of 0-2 and other evidence that the event was caused by focal ischemia

ABCD2 SCORE

  • Age > 60 (1 pt)
  • Blood pressure (SBP >140 OR diastolic >90) (1 pt)
  • Clinical Features
    • unilateral weakness (2 pt)
    • isolated speech disturbance (1 pt)
  • Duration of symptoms
    • >60 min (2 pt)
    • 10-59 min (1 pt)
  • Diabetes (1 pt)
Points
Risk
Two Days
Seven Days
90 Days
0-3
Low
1.0%
1.2%
3.1%
4-5
Moderate
4.1%
5.9%
9.8%
6-7
High
8.1%
11.7%
17.8%

None with score < 3 had CVA within one week in study

National Stroke Association

Hospitalization for pts with first TIA w/in past 24-48 hours, and is generally recommended for pts with the following conditions:

  1. Crescendo TIA
  2. Duration of symptoms > 1hr
  3. Symptomatic carotid stenosis > 50%
  4. Known cardiac source of embolus
  5. Known hypercoaguable state
  6. High risk of early stroke after TIA

TIA ADMIT (nmlly neg sy; <1hr)

  1. any Johnson criteria
  2. <1 wk from onset

See Also

CVA (Main)

Source

  • Stroke 2009;40[6]:2276