Iodoquinol

Administration

• Type: Amebicide
• Routes of Administration: Oral
• Common Trade Names: Aloquin; Yodoxin

Adult Dosing

• 650 mg 3 times daily after meals for 20 days
  • Not to exceed 1.95 g daily

Pediatric Dosing

• Children: 30-40 mg/kg daily (maximum: 650 mg per dose) in 3 divided doses for 20 days
  • Not to exceed 1.95 g daily

Special Populations

• Limited data on use during pregnancy

Renal Dosing

• No adjustments noted by manufacturer

Hepatic Dosing

• No adjustments noted by manufacturer

Contraindications

• Allergy to class/drug
• Concerns with optic neuritis
• Concerns with peripheral neuropathy

Adverse Reactions

• Nausea/vomiting
• Chills
• Fever
• Headache, vertigo
• Pruritus
• Thyroid gland enlargement
• Abdominal cramps
• Peripheral neuropathy
• Optic atrophy
• Optic neuritis

Pharmacology

• Half-life:
• Metabolism: Liver
• Excretion: Feces, urine

Mechanism of Action

It is a contact amebicide that works in the lumen of the intestine (unknown mechanism)

References

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