Osmolal or Osmolar Gap: Difference between revisions
No edit summary |
Neil.m.young (talk | contribs) No edit summary |
||
| Line 25: | Line 25: | ||
**[[Lactic acidosis]] | **[[Lactic acidosis]] | ||
**[[Chronic kidney disease]] | **[[Chronic kidney disease]] | ||
==See Also== | ==See Also== | ||
*[[Anion Gap and Osmolar Gap (High)]] | *[[Anion Gap and Osmolar Gap (High)]] | ||
==References== | |||
<references/> | |||
[[Category:FEN]] | [[Category:FEN]] | ||
[[Category:Tox]] | [[Category:Tox]] | ||
Revision as of 18:06, 19 February 2016
Definitions
- Osmolarity = the total number of particles in solution per liter
- Osmolality = the number of particles per kilogram of solvent
Calculations
Calculated Osm
Calculated Osm = 2 x Na + (glu/18) + (BUN/2.8) + (ethanol/4.6) + (methanol/2.6) + (ethylene glycol/5) + (acetone/5.5) + (isopropanol/5.9)
- Normal = 275-295
Osmolal Gap
- Osmolal Gap = measured osm - calculated osm
- Normal = (-)14-10 mOsm/L
DDx
- EtOH
- Ethylene glycol
- Methanol
- Isopropyl alcohol toxicity
- Diethylene glycol
- Propylene glycol
- Mannitol
- Glycerol
- Smaller gaps possible in:
- Ketoacidosis
- Lactic acidosis
- Chronic kidney disease