Succinylcholine: Difference between revisions
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==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*Lactation: | *Lactation: Unknown if compound is excreted in breast milk | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult | ||
Revision as of 04:26, 6 October 2015
See critical care quick reference for drug doses by weight.
General
- Type: Neuromuscular blocker
- Dosage Forms: IV or IM
- Common Trade Names: Anectine; Quelicin; Quelicin-1000
Adult Dosing
- 1.5 mg/kg IV
- 4 mg/kg IM (in extremis)
Pediatric Dosing
See critical care quick reference for drug doses by weight.
Special Populations
- Pregnancy Rating: C
- Lactation: Unknown if compound is excreted in breast milk
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Hyperkalemia
- Preexisting hyperkalemia
- Burns >5d old
- Crush injury >5d old
- Severe infection >5d old
- Neuromuscular diseases (e.g. Myasthenia Gravis), myopathies
- History of Malignant Hyperthermia
- Allergy to class/drug
Adverse Reactions
Serious
- Fatal hyperkalemia
- Malignant hyperthermia
- Masseter spasm
Common
Pharmacology
- Onset: 45-60 seconds
- Metabolism:
- Excretion:
- Mechanism of Action:
- Duration of Action: 5-10 minutes
See Also
Sources
- Levitan, R. Annals of EM. Vol 45, Issue 2. Safety of succinylcholine in myasthenia gravis.