Succinylcholine: Difference between revisions

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*Type: [[Neuromuscular blocker]]
*Type: [[Neuromuscular blocker]]
*Dosage Forms: IV or IM
*Dosage Forms: IV or IM
*Common Trade Names:
*Common Trade Names: Anectine; Quelicin; Quelicin-1000


==Adult Dosing==
==Adult Dosing==

Revision as of 04:23, 6 October 2015

See critical care quick reference for drug doses by weight.

General

Adult Dosing

  • 1.5 mg/kg IV
  • 4 mg/kg IM (in extremis)

Pediatric Dosing

See critical care quick reference for drug doses by weight.

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Hyperkalemia
  • Preexisting hyperkalemia
  • Burns >5d old
  • Crush injury >5d old
  • Severe infection >5d old
  • Neuromuscular diseases (e.g. Myasthenia Gravis), myopathies
  • History of Malignant Hyperthermia
  • Allergy to class/drug

Adverse Reactions

Serious

  • Fatal hyperkalemia
  • Malignant hyperthermia
  • Masseter spasm

Common

Pharmacology

  • Onset: 45-60 seconds
  • Metabolism:
  • Excretion:
  • Mechanism of Action:
  • Duration of Action: 5-10 minutes

See Also

Sources

  • Levitan, R. Annals of EM. Vol 45, Issue 2. Safety of succinylcholine in myasthenia gravis.