Acetazolamide: Difference between revisions
| Line 9: | Line 9: | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*[[Lactation risk categories|Lactation risk]]: | *[[Lactation risk categories|Lactation risk]]: Safe | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult: CrCl 10-50: give q12h; CrCl<10: avoid use; HD/PD: not defined | ||
**Pediatric | **Pediatric: CrCl 10-50: give q12h; CrCl<10: avoid use, HD/PD: not defined | ||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult: contraindicated in significant impairment/cirrhosis | ||
**Pediatric | **Pediatric: contraindicated in significant impairment/cirrhosis | ||
==Contraindications== | ==Contraindications== | ||
Revision as of 20:46, 26 June 2015
General
- Type: Carbonic anhydrase inhibitor
- Dosage Forms: PO/IV
- Common Trade Names: Diamox
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation risk: Safe
- Renal Dosing
- Adult: CrCl 10-50: give q12h; CrCl<10: avoid use; HD/PD: not defined
- Pediatric: CrCl 10-50: give q12h; CrCl<10: avoid use, HD/PD: not defined
- Hepatic Dosing
- Adult: contraindicated in significant impairment/cirrhosis
- Pediatric: contraindicated in significant impairment/cirrhosis
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: 10-15h
- Metabolism: CYP450
- Excretion: urine (100% unchanged)
- Mechanism of Action: inhibits carbonic anhydrase