Ricin: Difference between revisions
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*acute lung injury | *acute lung injury | ||
*Pulmonary edema may develop one to 3 days after exposure, | *Pulmonary edema may develop one to 3 days after exposure, | ||
**fever, cough, shortness of breath, and nausea. | **fever, cough, shortness of breath, and nausea. | ||
*symptoms and time to death were also dose related and associated with alveolar flooding, fibropurulent pneumonia, and necrotizing tracheitis | |||
*symptoms and time to death were also dose | |||
related and associated with alveolar flooding, fibropurulent | |||
pneumonia, and necrotizing tracheitis | |||
*Death 36-48 hours after exposure | *Death 36-48 hours after exposure | ||
Revision as of 02:00, 10 June 2015
Background
- Found in castor beans from the plant Ricinus communis
- A residual product of the production of castor oil (if properly prepared, does not contain the toxin)
Clinical Features
- Depends on type of exposure (parenteral, inhaled, or ingested)
- First symptoms occcur 3-12 hours after exposure
- Multiorgan failure occurred with a prominently elevated white blood cell count.
- acute lung injury
- Pulmonary edema may develop one to 3 days after exposure,
- fever, cough, shortness of breath, and nausea.
- symptoms and time to death were also dose related and associated with alveolar flooding, fibropurulent pneumonia, and necrotizing tracheitis
- Death 36-48 hours after exposure
Differential Diagnosis
Diagnosis
- Chest x-ray = bilateral infiltrates
Management
Disposition
See Also
External Links
References
- Lutwick LI,Gradon J, Zellen J: Category B Biotoxins. In Lutwick LI, Lutwick SM (eds), Beyond Anthrax: Bioterror - The Weaponization of Infectious Diseases. Springer-Humana, New York, 2009, New York, pp. 181-206: